The battle for Champions League football is growing fierce as Chelsea and Liverpool move within three points of Manchester United and Aston Villa.
Elsewhere, West Ham will look to claw their way out of the relegation zone, as Tottenham sit just one point above the drop.
Arsenal F.C vs Everton F.C – Saturday 5:30pm
Arsenal manager Mikel Arteta called for his side to “stay emotionally composed” after they rescued a 1-1 draw against Bayer Leverkusen in the Champions League midweek.
It will be the 149th fixture between the teams, with the Gunners winning on 103 occasions.
Notably, Arteta’s side is unbeaten in their last six matches against Everton and have not lost in the league since January 25.
Though the Toffees last won at the Emirates in April 2021, their strong away form may still concern the league leaders as they look to mount a challenge for European football.
Prediction: Under 2.5 goals in the game
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Chelsea F.C vs Newcastle United – Saturday 5:30pm
Chelsea have not won any of their last three meetings against Newcastle as the Blues remain locked in a tight battle for the top four.
Both sides were in action midweek. The Magpies held La Liga leaders Barcelona to a 1-1 draw at St James’ Park, while Chelsea slumped to a 5-2 defeat to PSG in the French capital.
Chelsea captain Reece James said his team “need to react” and that “there’s a lot to learn.”
Eddie Howe’s side have conceded in their last 14 games, which will encourage in-form forward João Pedro, who has 11 goal contributions in 10 appearances as his side looks to bounce back from their midweek disappointment.
Prediction: Chelsea to win and score over 1.5 goals
West Ham vs Manchester City – Saturday 8:00pm
Manchester City manager Pep Guardiola will serve a touchline ban against West Ham as assistant coach Pep Lijnders takes charge in the capital.
The Spaniard, for only the fifth time in his career, conceded three first-half goals as a manager as City were dominated by Real Madrid on Wednesday evening.
Despite being in the relegation zone, the Hammers have lost just two of their last 10 games and moved level with Forest on points last week.
Nuno Espírito Santo’s side have not beaten City in the league since September 2015 and face Erling Haaland, who has scored 11 goals against them — more than against any other English side.
Prediction: Over 4.5 goals in the game
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Crystal Palace vs Leeds United – Sunday 2:00pm
Despite being only three points above the relegation zone, Leeds will be confident as they travel to Selhurst Park.
A 4-1 victory at Elland Road earlier this season against the Eagles gives Daniel Farke’s side the opportunity to complete the league double over them for the first time since the 1994/95 season.
Palace’s form has dipped following European games, winning just once after midweek action.
Despite having over 70% possession, a 0-0 draw with AEK Larnaca in the Conference League meant Oliver Glasner’s side were left rueing their chances as they travel to Cyprus next week for the second leg.
Prediction: Crystal Palace to win
Manchester United vs Aston Villa – Sunday 2:00pm
Michael Carrick’s perfect start as United manager was halted by a late Newcastle winner as the Red Devils lost for the first time since January 11.
Against Villa, they have lost just two of their last 37 home games and have kept 30 clean sheets against them in the league. Only Arsenal have more (31) against a single opponent, against Newcastle.
Unai Emery’s side is hoping to complete the league double over United for the first time since the 1954/55 season, but three wins in their last 11 league games are a concern for the Champions League hopefuls.
The Spaniard insists they “are not feeling under pressure” despite only four sides picking up fewer points in that period.
Prediction: United to win by under 1.5 goals
Nottingham Forest vs Fulham F.C – Sunday 2:00pm
Fulham’s resurgent form has masked their poor defensive record, as they have conceded a goal in each of their last 14 matches.
However, Forest’s record against the Cottagers is poor, with just one win in seven Premier League games — a win rate of just 14%.
Vítor Pereira’s side are winless in six home games, only going longer without a victory at the City Ground in 1999.
Prediction: Fulham to win and score over 2.5 goals
Liverpool F.C vs Tottenham Hotspur – Sunday 4:30pm
After their 5-2 defeat to Atlético Madrid on Wednesday, Tottenham have lost six consecutive matches for the first time in their 143-year history.
Spurs have earned 19 of their 29 points away from home but have won just once in their last 31 visits to Anfield.
It is the highest-scoring Premier League fixture in history, with Liverpool scoring 127 of the 209 goals.
The Reds have lost one league game this season, more than their previous two campaigns combined, as they remain in the chase for Champions League football.
Prediction: Liverpool to win and both teams to score
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Brentford F.C vs Wolverhampton Wanderers – Monday 8:00pm
Wolves manager Rob Edwards wants his side to “keep things going and ride that wave” of momentum after his team claimed two successive league wins.
With just one win in their previous 32 league matches, Wolves could become the first side since Leicester City in 2015 to win three consecutive league games starting the day at the bottom of the table.
Brentford, meanwhile, are unbeaten in their last four games against Wolves and have not lost successive home games since February 2025.
Igor Thiago is the Bees’ top scorer and second in the league with 18 goals, four behind Manchester City’s Erling Haaland.
Prediction: Over 2.5 goals in the game
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SportJustSport writers 
Nicole Powell